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A-306989, an inhibitor of adenosine kinase, is renoprotective in rodent models of podocyte, basement membrane, and obstructive injury.
Zhu, Chang Z; Gopalakrishnan, Sujatha; Doyle, Kelly; Nikkel, Arthur L; Olson, Lauren; Abraham, Vivek C; Leys, Laura; Widomski, Deborah; Salte, Katherine; Putman, Brent; Pratt, Steve; Ma, Ji; Su, Zhi; Gopalakrishnan, Murali; Lee, Chih-Hung; McGaraughty, Steve P.
Affiliation
  • Zhu CZ; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA. Electronic address: chang.z.zhu@abbvie.com.
  • Gopalakrishnan S; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Doyle K; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Nikkel AL; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Olson L; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Abraham VC; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Leys L; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Widomski D; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Salte K; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Putman B; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Pratt S; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Ma J; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Su Z; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Gopalakrishnan M; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • Lee CH; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  • McGaraughty SP; Renal Research, Research and Development, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
Eur J Pharmacol ; 788: 1-11, 2016 Oct 05.
Article in En | MEDLINE | ID: mdl-27288879
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Basement Membrane / Adenosine Kinase / Cytoprotection / Protein Kinase Inhibitors / Podocytes / Kidney Aspects: Patient_preference Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2016 Document type: Article Country of publication: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Basement Membrane / Adenosine Kinase / Cytoprotection / Protein Kinase Inhibitors / Podocytes / Kidney Aspects: Patient_preference Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2016 Document type: Article Country of publication: Netherlands