Pseudomonal and candidal peritonitis as a complication of continuous ambulatory peritoneal dialysis in human immunodeficiency virus-infected patients.
Am J Med
; 86(6 Pt 2): 787-90, 1989 Jun.
Article
in En
| MEDLINE
| ID: mdl-2729340
ABSTRACT
PURPOSE:
To our knowledge, there has been no report documenting the spectrum of peritonitis in human immunodeficiency virus (HIV)-infected persons. We therefore analyzed our records to confirm our previous observation of a higher incidence of pseudomonal and fungal peritonitis in a group of HIV antibody-positive (HIV+) patients undergoing continuous ambulatory peritoneal dialysis (CAPD). PATIENTS ANDMETHODS:
During a 22-month period, we retrospectively studied 71 patients with end-stage renal disease undergoing CAPD. Of these, seven were HIV+, five were at high risk for HIV infection but antibody-negative, and 59 were at low risk for HIV infection. Organisms isolated in episodes of peritonitis were classified microbiologically as one of the following gram-positive, non-pseudomonal gram-negative, pseudomonal, fungal, or culture-negative.RESULTS:
The total peritonitis rate was higher in both the high-risk (p less than or equal to 0.01) and the HIV+ (p less than or equal to 0.02) groups when compared with that in the low-risk population. These differences were attributable to the following (1) the high-risk group's two-fold increase in gram-positive infections (p less than or equal to 0.01), and (2) a 24-fold increase in pseudomonal (p less than 0.001) infections and seven-fold increase in fungal (p less than 0.005) infections in the HIV+ group. These infections were invariably associated with catheter loss and frequently resulted in conversion to hemodialysis.CONCLUSION:
We believe that the use of CAPD in HIV+ patients may be limited by this increased occurrence of pseudomonal and fungal peritonitis.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Peritonitis
/
Pseudomonas Infections
/
Opportunistic Infections
/
Candidiasis
/
Acquired Immunodeficiency Syndrome
/
Peritoneal Dialysis, Continuous Ambulatory
Type of study:
Etiology_studies
/
Observational_studies
Limits:
Humans
Language:
En
Journal:
Am J Med
Year:
1989
Document type:
Article