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Maternal serum Netrin-1 levels as a new biomarker of preeclampsia.
Çekmez, Yasemin; Garip, Sebnem; Ulu, Ipek; Gülsen, Serdar; Haberal, Esra Tustas; Olgac, Yusuf; Yogurtçuoglu, Eser Evrim; Türkmen, Simge Bagci; Aksoy, Fatma Tutku; Kiran, Gürkan.
Affiliation
  • Çekmez Y; a Department of Obstetrics and Gyneacology , Health Sciences University Umraniye Medical and Research Hospital , Istanbul , Turkey.
  • Garip S; b Department of Biochemistry , Kemerburgaz University , Istanbul , Turkey , and.
  • Ulu I; a Department of Obstetrics and Gyneacology , Health Sciences University Umraniye Medical and Research Hospital , Istanbul , Turkey.
  • Gülsen S; a Department of Obstetrics and Gyneacology , Health Sciences University Umraniye Medical and Research Hospital , Istanbul , Turkey.
  • Haberal ET; a Department of Obstetrics and Gyneacology , Health Sciences University Umraniye Medical and Research Hospital , Istanbul , Turkey.
  • Olgac Y; c Department of Obstetrics and Gyneacology , Florence Nightingale Hospital , Istanbul , Turkey.
  • Yogurtçuoglu EE; a Department of Obstetrics and Gyneacology , Health Sciences University Umraniye Medical and Research Hospital , Istanbul , Turkey.
  • Türkmen SB; a Department of Obstetrics and Gyneacology , Health Sciences University Umraniye Medical and Research Hospital , Istanbul , Turkey.
  • Aksoy FT; b Department of Biochemistry , Kemerburgaz University , Istanbul , Turkey , and.
  • Kiran G; a Department of Obstetrics and Gyneacology , Health Sciences University Umraniye Medical and Research Hospital , Istanbul , Turkey.
J Matern Fetal Neonatal Med ; 30(9): 1072-1074, 2017 May.
Article in En | MEDLINE | ID: mdl-27296221
AIM: The aim of this study was to investigate whether the Netrin-1 levels in maternal serum was associated with the presence of preeclampsia (PE). METHODS: Total 72 patients, including 28 normal pregnant women and 44 patients with PE, were included in this study. Maternal serum Netrin-1 concentration was measured by enzyme-linked immunosorbent assay (ELISA). RESULTS: Maternal serum Netrin-1 levels were detected statistically higher in preeclamptic group than control group (p < 0.05). When compared with subgroups, Netrin-1 levels were also higher in severe PE group than mild PE group but this was not detected statistically significant (p > 0.05). CONCLUSION: Maternal serum Netrin-1 has a potential to be a new marker for the detection of PE.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pre-Eclampsia / Netrin-1 Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adult / Female / Humans / Pregnancy Language: En Journal: J Matern Fetal Neonatal Med Journal subject: OBSTETRICIA / PERINATOLOGIA Year: 2017 Document type: Article Affiliation country: Turkey Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pre-Eclampsia / Netrin-1 Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adult / Female / Humans / Pregnancy Language: En Journal: J Matern Fetal Neonatal Med Journal subject: OBSTETRICIA / PERINATOLOGIA Year: 2017 Document type: Article Affiliation country: Turkey Country of publication: United kingdom