Suppressive effect of epigallocatechin-3-O-gallate on endoglin molecular regulation in myocardial fibrosis in vitro and in vivo.

Lin, Chiu-Mei; Chang, Hang; Wang, Bao-Wei; Shyu, Kou-Gi

Lin, Chiu-Mei; Chang, Hang; Wang, Bao-Wei; Shyu, Kou-Gi.

Affiliation

Lin CM; Department of Emergency Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
Chang H; Faculty of Medicine, School of Medicine, Fu Jen Catholic University, Taipei, Taiwan.
Wang BW; Institute of Injury Prevention and Control, College of Public Health, Taipei Medical University, Taipei, Taiwan.
Shyu KG; Department of Emergency Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.

J Cell Mol Med ; 20(11): 2045-2055, 2016 11.

Article in En | MEDLINE | ID: mdl-27306149

Subject(s)

Catechin/analogs & derivatives; Endoglin/metabolism; Myocardium/metabolism; Myocardium/pathology; Angiotensin II/pharmacology; Animals; Anthracenes/pharmacology; Catechin/pharmacology; Cell Proliferation/drug effects; Cells, Cultured; Fibrosis; Heart Failure/complications; Heart Failure/metabolism; Heart Failure/pathology; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases/metabolism; Male; Models, Biological; Myocardial Infarction/complications; Myocardial Infarction/metabolism; Myocardial Infarction/pathology; Promoter Regions, Genetic/genetics; Protein Binding/drug effects; RNA, Small Interfering/metabolism; Rats, Wistar; Signal Transduction/drug effects; Transcription Factor AP-1/metabolism

Key words

EGCG; JNK; AP-1; angiotensin II; endoglin; myocardial fibrosis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Catechin / Endoglin / Myocardium Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2016 Document type: Article Affiliation country: Taiwan Country of publication: United kingdom

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