Establishment and characterization of a chordoma cell line from the tissue of a patient with dedifferentiated-type chordoma.

Kim, Jeong-Yub; Lee, Jongsun; Koh, Jae-Soo; Park, Myung-Jin; Chang, Ung-Kyu

Kim, Jeong-Yub; Lee, Jongsun; Koh, Jae-Soo; Park, Myung-Jin; Chang, Ung-Kyu.

Affiliation

Kim JY; Division of Radiation Cancer Research, Research Center for Radio-Senescence.
Lee J; Department of Pathology, College of Medicine, Korea University, Seoul, South Korea.
Koh JS; Division of Radiation Cancer Research, Research Center for Radio-Senescence.
Park MJ; Department of Pathology, and.
Chang UK; Division of Radiation Cancer Research, Research Center for Radio-Senescence.

J Neurosurg Spine ; 25(5): 626-635, 2016 Nov.

Article in En | MEDLINE | ID: mdl-27314550

Subject(s)

Cell Line, Tumor; Chordoma; Animals; Cell Culture Techniques; Cell Survival/drug effects; Cell Survival/radiation effects; Chordoma/pathology; Chordoma/physiopathology; Chordoma/surgery; Coccyx; Female; Humans; Mice, Nude; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Transplantation; Spinal Neoplasms/pathology; Spinal Neoplasms/physiopathology; Spinal Neoplasms/surgery

Key words

CXCR4; DTC = dedifferentiated-type chordoma; EGFR = epidermal growth factor receptor; EMT = epithelial to mesenchymal transition; FACS = fluorescence-activated cell sorting; FBS = fetal bovine serum; IR = ionizing radiation; PBS = phosphate-buffered saline; PDGFR = platelet-derived growth factor receptor; PTEN = phosphatase and tensin homolog; RT = room temperature; TBST = Tris-buffered saline with Tween 20; brachyury; chordoma; dedifferentiated-type chordoma; oncology; p- = phosphorylated

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Collection: 01-internacional Database: MEDLINE Main subject: Chordoma / Cell Line, Tumor Limits: Animals / Female / Humans / Middle aged Language: En Journal: J Neurosurg Spine Journal subject: NEUROCIRURGIA Year: 2016 Document type: Article Country of publication: United States

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