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Prostaglandin EP2 receptor signaling protects human trabecular meshwork cells from apoptosis induced by ER stress through down-regulation of p53.
Kalouche, Georges; Boucher, Céline; Coste, Annick; Debussche, Laurent; Orsini, Cécile; Baudouin, Christophe; Debeir, Thomas; Vigé, Xavier; Rostène, William.
Affiliation
  • Kalouche G; Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, 75012 Paris, France; Sanofi Research & Development, Translational Sciences Unit, Chilly-Mazarin 91380, France. Electronic address: georges.kalouche@sanofi.com.
  • Boucher C; Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, 75012 Paris, France.
  • Coste A; Sanofi Research & Development, Translational Sciences Unit, Chilly-Mazarin 91380, France.
  • Debussche L; Sanofi Research & Development, Oncology, Vitry-Sur-Seine 94400, France.
  • Orsini C; Sanofi Research & Development, Translational Sciences Unit, Chilly-Mazarin 91380, France.
  • Baudouin C; Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, 75012 Paris, France; Quinze-Vingts National Ophthalmology Hospital, Paris 75012, France.
  • Debeir T; Sanofi Research & Development, Ophthalmology, Paris 75012, France.
  • Vigé X; Sanofi Research & Development, Translational Sciences Unit, Chilly-Mazarin 91380, France.
  • Rostène W; Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, 75012 Paris, France.
Biochim Biophys Acta ; 1863(9): 2322-32, 2016 09.
Article in En | MEDLINE | ID: mdl-27321910
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trabecular Meshwork / Signal Transduction / Down-Regulation / Tumor Suppressor Protein p53 / Apoptosis / Cytoprotection / Receptors, Prostaglandin E, EP2 Subtype / Endoplasmic Reticulum Stress Type of study: Prognostic_studies Limits: Adult / Humans / Male Language: En Journal: Biochim Biophys Acta Year: 2016 Document type: Article Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trabecular Meshwork / Signal Transduction / Down-Regulation / Tumor Suppressor Protein p53 / Apoptosis / Cytoprotection / Receptors, Prostaglandin E, EP2 Subtype / Endoplasmic Reticulum Stress Type of study: Prognostic_studies Limits: Adult / Humans / Male Language: En Journal: Biochim Biophys Acta Year: 2016 Document type: Article Country of publication: Netherlands