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Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Li, Sheng; Garrett-Bakelman, Francine E; Chung, Stephen S; Sanders, Mathijs A; Hricik, Todd; Rapaport, Franck; Patel, Jay; Dillon, Richard; Vijay, Priyanka; Brown, Anna L; Perl, Alexander E; Cannon, Joy; Bullinger, Lars; Luger, Selina; Becker, Michael; Lewis, Ian D; To, Luen Bik; Delwel, Ruud; Löwenberg, Bob; Döhner, Hartmut; Döhner, Konstanze; Guzman, Monica L; Hassane, Duane C; Roboz, Gail J; Grimwade, David; Valk, Peter J M; D'Andrea, Richard J; Carroll, Martin; Park, Christopher Y; Neuberg, Donna; Levine, Ross; Melnick, Ari M; Mason, Christopher E.
Affiliation
  • Li S; Department of Physiology and Biophysics and the HRH Prince Alwaleed Bin Talal Bin Abdulaziz Al-Saud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, New York, USA.
  • Garrett-Bakelman FE; Division of Hematology-Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
  • Chung SS; Leukemia Service, Department of Medicine, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Sanders MA; Erasmus University Medical Center, Department of Hematology, Rotterdam, the Netherlands.
  • Hricik T; Leukemia Service, Department of Medicine, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Rapaport F; Leukemia Service, Department of Medicine, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Patel J; Leukemia Service, Department of Medicine, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Dillon R; Department of Medical and Molecular Genetics, King's College London, Faculty of Life Sciences and Medicine, London, UK.
  • Vijay P; Tri-Institutional Training Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, New York, USA.
  • Brown AL; Center for Cancer Biology, SA Pathology and University of South Australia, Adelaide, South Australia, Australia.
  • Perl AE; School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia, Australia.
  • Cannon J; Department of Hematology, SA Pathology and Royal Adelaide Hospital, Adelaide, South Australia, Australia.
  • Bullinger L; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Luger S; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Becker M; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.
  • Lewis ID; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • To LB; University of Rochester Medical Center, Rochester, New York, USA.
  • Delwel R; Center for Cancer Biology, SA Pathology and University of South Australia, Adelaide, South Australia, Australia.
  • Löwenberg B; Department of Hematology, SA Pathology and Royal Adelaide Hospital, Adelaide, South Australia, Australia.
  • Döhner H; School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
  • Döhner K; Department of Hematology, SA Pathology and Royal Adelaide Hospital, Adelaide, South Australia, Australia.
  • Guzman ML; School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
  • Hassane DC; Erasmus University Medical Center, Department of Hematology, Rotterdam, the Netherlands.
  • Roboz GJ; Erasmus University Medical Center, Department of Hematology, Rotterdam, the Netherlands.
  • Grimwade D; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.
  • Valk PJ; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.
  • D'Andrea RJ; Division of Hematology-Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
  • Carroll M; Division of Hematology-Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
  • Park CY; Division of Hematology-Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
  • Neuberg D; Department of Medical and Molecular Genetics, King's College London, Faculty of Life Sciences and Medicine, London, UK.
  • Levine R; Erasmus University Medical Center, Department of Hematology, Rotterdam, the Netherlands.
  • Melnick AM; Center for Cancer Biology, SA Pathology and University of South Australia, Adelaide, South Australia, Australia.
  • Mason CE; School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia, Australia.
Nat Med ; 22(7): 792-9, 2016 07.
Article in En | MEDLINE | ID: mdl-27322744

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Gene Expression Regulation, Leukemic / Genetic Heterogeneity / Epigenesis, Genetic Type of study: Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2016 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Gene Expression Regulation, Leukemic / Genetic Heterogeneity / Epigenesis, Genetic Type of study: Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2016 Document type: Article Affiliation country: United States Country of publication: United States