Loss of laminin alpha 1 results in multiple structural defects and divergent effects on adhesion during vertebrate optic cup morphogenesis.

Bryan, Chase D; Chien, Chi-Bin; Kwan, Kristen M

Bryan, Chase D; Chien, Chi-Bin; Kwan, Kristen M.

Affiliation

Bryan CD; Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA.
Chien CB; Department of Neurobiology and Anatomy, University of Utah, Salt Lake City, UT 84112, USA.
Kwan KM; Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA. Electronic address: kristen.kwan@genetics.utah.edu.

Dev Biol ; 416(2): 324-37, 2016 08 15.

Article in En | MEDLINE | ID: mdl-27339294

Subject(s)

Eye Proteins/physiology; Laminin/physiology; Lens, Crystalline/embryology; Retina/embryology; Zebrafish Proteins/physiology; Zebrafish/embryology; Animals; Cell Movement; Cell Polarity; Extracellular Matrix/physiology; Eye Proteins/genetics; Focal Adhesions; Laminin/deficiency; Laminin/genetics; Luminescent Proteins/analysis; Luminescent Proteins/genetics; Microscopy, Confocal; Organogenesis; Retina/cytology; Retinal Ganglion Cells/cytology; Retinal Pigment Epithelium/cytology; Retinal Pigment Epithelium/embryology; Time-Lapse Imaging; Zebrafish Proteins/deficiency; Zebrafish Proteins/genetics

Key words

Adhesion; Cell polarity; Eye morphogenesis; Laminin; Lens; Retina

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retina / Zebrafish / Laminin / Zebrafish Proteins / Eye Proteins / Lens, Crystalline Limits: Animals Language: En Journal: Dev Biol Year: 2016 Document type: Article Affiliation country: United States Country of publication: United States

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