Cognitive Functioning and Academic Achievement in Children Aged 6-8 Years, Born at Term After Intrauterine Growth Restriction and Fetal Cerebral Redistribution.
J Pediatr Psychol
; 42(3): 345-354, 2017 Apr 01.
Article
in En
| MEDLINE
| ID: mdl-27342302
ABSTRACT
Objective:
To determine whether cerebroplacental ratio, an indicator of fetal cerebral redistribution (FCR), predicts adverse results for neurodevelopment in intrauterine growth restriction (IUGR) infants.Methods:
In a cohort of 5,702 infants, 64 were IUGR born at term with FCR. Five were excluded. Of the remainder, 32 presented an abnormal cerebroplacental ratio (IUGR-A) and 27 a normal one (IUGR-B). The controls were 61 appropriate-for-gestational-age children. Cognitive and academic outcomes and the odds ratio of lower academic scores were assessed by multivariate analysis of covariance and logistic regression.Results:
IUGR-A children presented deficits in cognitive functioning and academic achievement in all domains. IUGR-B children presented slight deficits. Suboptimal cognitive functioning in IUGR-A was more marked in working memory. Abnormal cerebroplacental ratio predicted low academic scores in IUGR-A.Conclusions:
FCR is a risk factor for IUGR infants, and cerebroplacental ratio identifies those most severely affected. Intervention programs may produce benefits in early-middle childhood.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Achievement
/
Umbilical Arteries
/
Cerebral Arteries
/
Cognition Disorders
/
Educational Status
/
Fetal Growth Retardation
Type of study:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Child
/
Female
/
Humans
/
Male
/
Newborn
Language:
En
Journal:
J Pediatr Psychol
Year:
2017
Document type:
Article
Affiliation country:
Spain