Nutraceutical therapies for atherosclerosis.
Nat Rev Cardiol
; 13(9): 513-32, 2016 09.
Article
in En
| MEDLINE
| ID: mdl-27383080
ABSTRACT
Atherosclerosis is a chronic inflammatory disease affecting large and medium arteries and is considered to be a major underlying cause of cardiovascular disease (CVD). Although the development of pharmacotherapies to treat CVD has contributed to a decline in cardiac mortality in the past few decades, CVD is estimated to be the cause of one-third of deaths globally. Nutraceuticals are natural nutritional compounds that are beneficial for the prevention or treatment of disease and, therefore, are a possible therapeutic avenue for the treatment of atherosclerosis. The purpose of this Review is to highlight potential nutraceuticals for use as antiatherogenic therapies with evidence from in vitro and in vivo studies. Furthermore, the current evidence from observational and randomized clinical studies into the role of nutraceuticals in preventing atherosclerosis in humans will also be discussed.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Arteries
/
Dietary Supplements
/
Atherosclerosis
/
Plaque, Atherosclerotic
/
Anti-Inflammatory Agents
/
Antioxidants
Type of study:
Clinical_trials
Limits:
Animals
/
Humans
Language:
En
Journal:
Nat Rev Cardiol
Journal subject:
CARDIOLOGIA
Year:
2016
Document type:
Article
Affiliation country:
United kingdom