High-Resolution Three-Dimensional Computed Tomography for Assessing Complications Related to Intrathecal Drug Delivery.
Pain Physician
; 19(5): E775-80, 2016 07.
Article
in En
| MEDLINE
| ID: mdl-27389121
ABSTRACT
BACKGROUND:
The assessment of the functionality of intrathecal drug delivery (IDD) systems remains difficult and time-consuming. Catheter-related problems are still very common, and sometimes difficult to diagnose.OBJECTIVES:
The aim of the present study is to investigate the accuracy of high-resolution three-dimensional computed tomography (CT) in order to detect catheter-related pump dysfunction. STUDYDESIGN:
An observational, retrospective investigation.SETTING:
Academic medical center in Germany.METHODS:
We used high-resolution three dimensional (3D) computed tomography with volume rendering technique (VRT) or fluoroscopy and conventional axial-CT to assess IDD-related complications in 51 patients from our institution who had IDD systems implanted for the treatment of chronic pain or spasticity.RESULTS:
Twelve patients (23.5%) presented a total of 22 complications. The main type of complication in our series was catheter-related (50%), followed by pump failure, infection, and inappropriate refilling. Fluoroscopy and conventional CT were used in 12 cases. High-resolution 3D CT VRT scan was used in 35 instances with suspected yet unclear complications. Using 3D-CT (VRT) the sensitivity was 58.93% - 100% (CI 95%) and the specificity 87.54% - 100% (CI 95%).The positive predictive value was 58.93% - 100% (CI 95%) and the negative predictive value 87.54% - 100% (CI 95%).Fluoroscopy and axial CT as a combined diagnostic tool had a sensitivity of 8.3% - 91.7% (CI 95%) and a specificity of 62.9% - 100% (CI 95%). The positive predictive value was 19.29% - 100% (CI 95%) and the negative predictive value 44.43% - 96.89% (CI 95%).LIMITATIONS:
This study is limited by its observational design and the small number of cases.CONCLUSION:
High-resolution 3D CT VRT is a non- invasive method that can identify IDD-related complications with more precision than axial CT and fluoroscopy.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Postoperative Complications
/
Infusion Pumps
/
Tomography, X-Ray Computed
/
Imaging, Three-Dimensional
/
Catheters
/
Infusions, Spinal
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
En
Journal:
Pain Physician
Journal subject:
PSICOFISIOLOGIA
Year:
2016
Document type:
Article
Affiliation country:
Germany