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Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases.
Sommer, Ann-Katrin; Hermawan, Adam; Mickler, Frauke Martina; Ljepoja, Bojan; Knyazev, Pjotr; Bräuchle, Christoph; Ullrich, Axel; Wagner, Ernst; Roidl, Andreas.
Affiliation
  • Sommer AK; Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Hermawan A; Department of Molecular Biology, Max-Planck-Institute of Biochemistry, 82152 Martinsried, Germany.
  • Mickler FM; Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Ljepoja B; Physical Chemistry, Department of Chemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Knyazev P; Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Bräuchle C; Department of Molecular Biology, Max-Planck-Institute of Biochemistry, 82152 Martinsried, Germany.
  • Ullrich A; Physical Chemistry, Department of Chemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Wagner E; Department of Molecular Biology, Max-Planck-Institute of Biochemistry, 82152 Martinsried, Germany.
  • Roidl A; Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
Oncotarget ; 7(31): 50461-50476, 2016 Aug 02.
Article in En | MEDLINE | ID: mdl-27409163

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrans / Tamoxifen / Breast Neoplasms / Receptor Protein-Tyrosine Kinases / Lysosomes Limits: Female / Humans Language: En Journal: Oncotarget Year: 2016 Document type: Article Affiliation country: Germany Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrans / Tamoxifen / Breast Neoplasms / Receptor Protein-Tyrosine Kinases / Lysosomes Limits: Female / Humans Language: En Journal: Oncotarget Year: 2016 Document type: Article Affiliation country: Germany Country of publication: United States