Cherubism. A case report.
Reumatol Clin
; 13(6): 352-353, 2017.
Article
in En, Es
| MEDLINE
| ID: mdl-27427211
ABSTRACT
Cherubism is a rare disorder with autosomal dominant inheritance. It is classified as a benign fibro-osseous lesions and may involve either facial bone. Its typical dentofacial deformities are caused by mutations in the SH3BP2 gene. The protein encoded by SH3BP2 had a significant role in the regulation of osteoblasts and osteoclasts. Accordingly with the radiological findings, differential diagnoses includes fibrous dysplasia, giant cell granuloma, osteosarcoma, juvenile ossifying fibroma, fibrous osteoma, odontogenic cyst and hyperparathyroidism. The aim of the present report is twofold. First, we examine the importance of the proper management of these cases. Second, we describe this rare syndrome with the goal of proposing suitable treatments.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cherubism
Type of study:
Diagnostic_studies
Limits:
Child
/
Humans
/
Male
Language:
En
/
Es
Journal:
Reumatol Clin
Year:
2017
Document type:
Article