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Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer.
Villano, Valentina; Di Stadio, Chiara Stella; Federico, Antonella; Altieri, Filomena; Miselli, Giuseppina; De Palma, Maurizio; Rippa, Emilia; Arcari, Paolo.
Affiliation
  • Villano V; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy.
  • Di Stadio CS; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy.
  • Federico A; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy.
  • Altieri F; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy.
  • Miselli G; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy.
  • De Palma M; Hospital A. Cardarelli, Nasples, Italy.
  • Rippa E; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy. emilia.rippa@unina.it.
  • Arcari P; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy. paolo.arcari@unina.it.
J Negat Results Biomed ; 15(1): 14, 2016 Jul 25.
Article in En | MEDLINE | ID: mdl-27452910
ABSTRACT

BACKGROUND:

We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease.

RESULTS:

Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), performed by using absolute quantification based on standard curve method, did not show any significative statistical difference between the two unpaired group of individuals.

CONCLUSIONS:

Our preliminary results did not confirm GKN1 as a potential biomarker for gastric cancer.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Biomarkers, Tumor / Peptide Hormones Type of study: Observational_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: J Negat Results Biomed Year: 2016 Document type: Article Affiliation country: Italy
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Biomarkers, Tumor / Peptide Hormones Type of study: Observational_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: J Negat Results Biomed Year: 2016 Document type: Article Affiliation country: Italy