Wegener's granulomatosis: treatment failure on conventional therapy.
J Rheumatol
; 16(4): 544-6, 1989 Apr.
Article
in En
| MEDLINE
| ID: mdl-2746596
ABSTRACT
We report a patient with Wegener's granulomatosis who was initially stabilized, but later relapsed with multiorgan involvement while taking high oral doses of cyclophosphamide (3.7 mg/kg body weight/day) and prednisolone. Remission was achieved with a combined therapy consisting of intermittent intravenous boluses of cyclophosphamide, oral prednisolone, plasmapheresis and oral trimethoprim-sulfamethoxazole. Discussion includes evaluation of the relative beneficial effect of the four treatment constituents.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Granulomatosis with Polyangiitis
Limits:
Adult
/
Humans
/
Male
Language:
En
Journal:
J Rheumatol
Year:
1989
Document type:
Article
Affiliation country:
Sweden