[Mesenchymal tumors of the mediastinum]. / Mesenchymale Tumoren des Mediastinums.
Pathologe
; 37(5): 449-56, 2016 Sep.
Article
in De
| MEDLINE
| ID: mdl-27488616
ABSTRACT
Mesenchymal neoplasms of the thymus and mediastinum account for only 2 % of neoplasms of the mediastinum and are therefore very rare. With very few exceptions the histology, immunohistochemistry and (based on current knowledge) molecular biology of mediastinal soft tissue tumors are not different from their counterparts in other organs. Characteristic features are more concerned with clinical epidemiological and therapeutic aspects as well as the multitude of possible differential diagnoses. With the exception of organ-specific tumors, such as gastrointestinal stromal tumors (GIST), virtually all entities encountered in peripheral soft tissues can also arise in the mediastinum. Primary mediastinal soft tissue sarcomas (STS) must be distinguished from secondary radiation-induced STS after irradiation, e. g. for breast cancer and Hodgkin's lymphoma and from STS arising as somatic type malignancies in mediastinal germ cell tumors.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Mediastinal Neoplasms
/
Mesenchymoma
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Humans
Language:
De
Journal:
Pathologe
Year:
2016
Document type:
Article