Significance of masked and nocturnal hypertension in normotensive women coursing a high-risk pregnancy.
J Hypertens
; 34(11): 2248-52, 2016 11.
Article
in En
| MEDLINE
| ID: mdl-27490952
ABSTRACT
OBJECTIVE:
The aim was to evaluate the prevalence of nocturnal and masked hypertension and the prognostic values of these blood pressure (BP) abnormalities in normotensive women coursing a high-risk pregnancy.METHODS:
The study was performed in pregnant women with 20 or more weeks of gestation coursing a high-risk pregnancy, sent to a specialized hypertension department to perform a prospective defined protocol of BP evaluation. Women with office BP at least 140/90âmmHg were excluded. An ambulatory monitoring of BP was performed to identify masked and nocturnal hypertension (defined according to the current guidelines). The adjusted risk for development of preeclampsia/eclampsia (PEEC) was estimated using logistic regression. The ability of SBP and DBP to identify risk of PEEC was estimated using area under the receiver-operating characteristic curves.RESULTS:
Eighty-seven women (29â±â7 years old, 30â±â5 weeks of pregnancy) were included in this analysis. The prevalence of masked hypertension was 33.3%. Nocturnal hypertension was found in 42.5% of the women. Remarkably, 27.0% of the women with nocturnal hypertension had normal 24-h values according to ambulatory BP monitoring. Twenty-two patients developed PEEC; adjusted relative risks increased with the presence of nocturnal (odds ratioâ=â4.72, 95% confidence interval 1.25-19.43, Pâ=â0.023) or masked hypertension (odds ratioâ=â7.81, 95% confidence interval 2.6-22.86, Pâ=â0.001). Nocturnal SBP and DBP had the highest abilities to predict PEEC (area under the curveâ=â0.77 and 0.80, respectively).CONCLUSION:
Masked and nocturnal hypertension are frequent findings in normotensive women coursing a high-risk pregnancy, and their presence implies an increased risk to develop PEEC.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pregnancy, High-Risk
/
Hypertension, Pregnancy-Induced
Type of study:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
J Hypertens
Year:
2016
Document type:
Article
Affiliation country:
Argentina