Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity.

Williams, Charles A C; Fernandez-Alonso, Rosalia; Wang, Jinhua; Toth, Rachel; Gray, Nathanael S; Findlay, Greg M

Williams, Charles A C; Fernandez-Alonso, Rosalia; Wang, Jinhua; Toth, Rachel; Gray, Nathanael S; Findlay, Greg M.

Affiliation

Williams CA; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Fernandez-Alonso R; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Wang J; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Toth R; The Division of Signal Transduction Therapy, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Gray NS; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Findlay GM; The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK. Electronic address: g.m.findlay@dundee.ac.uk.

Cell Rep ; 16(7): 1820-8, 2016 08 16.

Article in En | MEDLINE | ID: mdl-27498864

Subject(s)

Mitogen-Activated Protein Kinase 7/genetics; Mouse Embryonic Stem Cells/metabolism; Nuclear Proteins/genetics; Pluripotent Stem Cells/metabolism; Transcription Factors/genetics; Animals; Benzodiazepinones/pharmacology; CRISPR-Cas Systems; Cell Differentiation; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferases/genetics; DNA (Cytosine-5-)-Methyltransferases/metabolism; Embryoid Bodies/cytology; Embryoid Bodies/metabolism; Gene Editing; Gene Expression Regulation; Mice; Mitogen-Activated Protein Kinase 7/antagonists & inhibitors; Mitogen-Activated Protein Kinase 7/metabolism; Mouse Embryonic Stem Cells/cytology; Mouse Embryonic Stem Cells/drug effects; Myocytes, Cardiac/cytology; Myocytes, Cardiac/metabolism; Nanog Homeobox Protein/genetics; Nanog Homeobox Protein/metabolism; Neural Plate/cytology; Neural Plate/metabolism; Nuclear Proteins/metabolism; Pluripotent Stem Cells/cytology; Pluripotent Stem Cells/drug effects; Protein Kinase Inhibitors/pharmacology; Signal Transduction; Transcription Factors/metabolism; DNA Methyltransferase 3B

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Nuclear Proteins / Pluripotent Stem Cells / Mitogen-Activated Protein Kinase 7 / Mouse Embryonic Stem Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Rep Year: 2016 Document type: Article Affiliation country: United kingdom Country of publication: United States

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