The AMPK Activator Aicar Ameliorates Age-Dependent Myocardial Injury in Murine Hemorrhagic Shock.

Matsiukevich, Dzmitry; Piraino, Giovanna; Klingbeil, Lindsey R; Hake, Paul W; Wolfe, Vivian; O'Connor, Michael; Zingarelli, Basilia

Matsiukevich, Dzmitry; Piraino, Giovanna; Klingbeil, Lindsey R; Hake, Paul W; Wolfe, Vivian; O'Connor, Michael; Zingarelli, Basilia.

Affiliation

Matsiukevich D; *Department of Pediatrics, Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OhioDepartment of Surgery, University of Cincinnati, Cincinnati, Ohio.

Shock ; 47(1): 70-78, 2017 01.

Article in En | MEDLINE | ID: mdl-27513082

Subject(s)

AMP-Activated Protein Kinases/metabolism; Aminoimidazole Carboxamide/analogs & derivatives; Myocardium/metabolism; Ribonucleotides/therapeutic use; Shock, Hemorrhagic/drug therapy; Shock, Hemorrhagic/metabolism; Age Factors; Aminoimidazole Carboxamide/therapeutic use; Animals; Biomarkers/metabolism; Blotting, Western; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Mitochondria/drug effects; Mitochondria/metabolism; Myocardium/ultrastructure

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ribonucleotides / Shock, Hemorrhagic / AMP-Activated Protein Kinases / Aminoimidazole Carboxamide / Myocardium Limits: Animals Language: En Journal: Shock Journal subject: ANGIOLOGIA / CARDIOLOGIA Year: 2017 Document type: Article Country of publication: United States

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