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Pharmacological inhibition of protein kinase C (PKC)ζ downregulates the expression of cytokines involved in the pathogenesis of chronic obstructive pulmonary disease (COPD).
Abdel-Halim, Mohammad; Darwish, Sarah S; ElHady, Ahmed K; Hoppstädter, Jessica; Abadi, Ashraf H; Hartmann, Rolf W; Kiemer, Alexandra K; Engel, Matthias.
Affiliation
  • Abdel-Halim M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
  • Darwish SS; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
  • ElHady AK; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
  • Hoppstädter J; Pharmaceutical Biology, Saarland University, Saarbrücken, Germany.
  • Abadi AH; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
  • Hartmann RW; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany.
  • Kiemer AK; Pharmaceutical Biology, Saarland University, Saarbrücken, Germany.
  • Engel M; Pharmaceutical and Medicinal Chemistry, Saarland University, Saarbrücken, Germany. Electronic address: ma.engel@mx.uni-saarland.de.
Eur J Pharm Sci ; 93: 405-9, 2016 Oct 10.
Article in En | MEDLINE | ID: mdl-27516147
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Protein Kinase C / Gene Expression Regulation / Cytokines / Pulmonary Disease, Chronic Obstructive / Protein Kinase Inhibitors Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Eur J Pharm Sci Journal subject: FARMACIA / FARMACOLOGIA / QUIMICA Year: 2016 Document type: Article Affiliation country: Egypt Country of publication: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Protein Kinase C / Gene Expression Regulation / Cytokines / Pulmonary Disease, Chronic Obstructive / Protein Kinase Inhibitors Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Eur J Pharm Sci Journal subject: FARMACIA / FARMACOLOGIA / QUIMICA Year: 2016 Document type: Article Affiliation country: Egypt Country of publication: Netherlands