A comparative study of negative pressure wound therapy with and without instillation of saline on wound healing.
J Wound Care
; 25(8): 475-8, 2016 Aug.
Article
in En
| MEDLINE
| ID: mdl-27523660
ABSTRACT
OBJECTIVE:
Negative pressure wound therapy (NPWT) has become an established treatment of traumatic and infected wounds. Negative pressure wound therapy with instillation (NPWTi) is a further development that combines the conventional NPWT with instillation of different fluids which continuously administer therapeutic reagents to the wound. The aim of this study was to compare the impact of additional saline instillation in NPWTi to NPWT alone.METHOD:
Between January and July 2014, consecutive patients with acute wounds of the lower limb were treated with NPWTi with saline instillation. The number of revision surgeries, length of hospital stay, and duration of treatment until final healing were recorded and compared with matched patients undergoing NPWT without instillation.RESULTS:
There were 10 patients recruited with 10 matched controls examined restrospectivley. Patients who received NPWTi were found to have decreased time of hospitalisation (21.5 versus 26.5 days, p=0.43), and accelerated wound healing (9.0 versus 12.5 days, p=0.36) than patients who received NPWT. However, the difference in the outcomes of the patients who received NPWTi and patients who received NPWT was not found to be statisticallly significant.CONCLUSION:
NPWTi with instillation of saline is a promising method and its effectiveness needs to be tested in a randomised controlled trial compared with NPWT alone. DECLARATION OF INTEREST This study obtained support by KCI (Wiebsaden, Germany) for the surgical material.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Wound Healing
/
Wound Infection
/
Wounds and Injuries
/
Sodium Chloride
/
Negative-Pressure Wound Therapy
/
Therapeutic Irrigation
Type of study:
Clinical_trials
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
En
Journal:
J Wound Care
Journal subject:
ENFERMAGEM
Year:
2016
Document type:
Article