Immunological evaluation of colonic delivered Hepatitis B surface antigen loaded TLR-4 agonist modified solid fat nanoparticles.

Sahu, Kantrol Kumar; Pandey, Ravi Shankar

Sahu, Kantrol Kumar; Pandey, Ravi Shankar.

Affiliation

Sahu KK; SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya, Bilaspur, C.G. 495001, India.
Pandey RS; SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya, Bilaspur, C.G. 495001, India. Electronic address: ravishankarpandey2@rediffmail.com.

Int Immunopharmacol ; 39: 343-352, 2016 Oct.

Article in En | MEDLINE | ID: mdl-27526270

Subject(s)

Hepatitis B Surface Antigens/immunology; Hepatitis B Vaccines/administration & dosage; Hepatitis B virus/immunology; Hepatitis B/prevention & control; Lipid A/analogs & derivatives; Nanoparticles/administration & dosage; Administration, Rectal; Animals; Cells, Cultured; Hepatitis B/immunology; Hepatitis B Surface Antigens/chemistry; Immunity, Mucosal; Immunoglobulin A/blood; Interferon-gamma/metabolism; Interleukin-2/metabolism; Lipid A/chemistry; Lipid A/immunology; Lipid A/pharmacology; Lymphocyte Activation; Nanoparticles/chemistry; Rats; Rats, Sprague-Dawley; Th1 Cells/immunology; Th2 Cells/immunology; Toll-Like Receptor 4/agonists

Key words

Colon delivered vaccine; HBsAg; Mucosal immunity; Nanoparticle

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis B virus / Hepatitis B Vaccines / Nanoparticles / Hepatitis B / Hepatitis B Surface Antigens / Lipid A Limits: Animals Language: En Journal: Int Immunopharmacol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Year: 2016 Document type: Article Affiliation country: India

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