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msBiodat analysis tool, big data analysis for high-throughput experiments.
Muñoz-Torres, Pau M; Rokc, Filip; Beluzic, Robert; Grbesa, Ivana; Vugrek, Oliver.
Affiliation
  • Muñoz-Torres PM; Translational Medicine Group, Institut Rudjer Boskovic, Division of Molecular Medicine, Bijenicka Cesta 54, Zagreb, 10000 Croatia.
  • Rokc F; Translational Medicine Group, Institut Rudjer Boskovic, Division of Molecular Medicine, Bijenicka Cesta 54, Zagreb, 10000 Croatia.
  • Beluzic R; Translational Medicine Group, Institut Rudjer Boskovic, Division of Molecular Medicine, Bijenicka Cesta 54, Zagreb, 10000 Croatia.
  • Grbesa I; Translational Medicine Group, Institut Rudjer Boskovic, Division of Molecular Medicine, Bijenicka Cesta 54, Zagreb, 10000 Croatia.
  • Vugrek O; Translational Medicine Group, Institut Rudjer Boskovic, Division of Molecular Medicine, Bijenicka Cesta 54, Zagreb, 10000 Croatia.
BioData Min ; 9: 26, 2016.
Article in En | MEDLINE | ID: mdl-27547241
BACKGROUND: Mass spectrometry (MS) are a group of a high-throughput techniques used to increase knowledge about biomolecules. They produce a large amount of data which is presented as a list of hundreds or thousands of proteins. Filtering those data efficiently is the first step for extracting biologically relevant information. The filtering may increase interest by merging previous data with the data obtained from public databases, resulting in an accurate list of proteins which meet the predetermined conditions. RESULTS: In this article we present msBiodat Analysis Tool, a web-based application thought to approach proteomics to the big data analysis. With this tool, researchers can easily select the most relevant information from their MS experiments using an easy-to-use web interface. An interesting feature of msBiodat analysis tool is the possibility of selecting proteins by its annotation on Gene Ontology using its Gene Id, ensembl or UniProt codes. CONCLUSION: The msBiodat analysis tool is a web-based application that allows researchers with any programming experience to deal with efficient database querying advantages. Its versatility and user-friendly interface makes easy to perform fast and accurate data screening by using complex queries. Once the analysis is finished, the result is delivered by e-mail. msBiodat analysis tool is freely available at http://msbiodata.irb.hr.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioData Min Year: 2016 Document type: Article Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioData Min Year: 2016 Document type: Article Country of publication: United kingdom