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Gastric carcinoma in canines and humans, a review.
Hugen, S; Thomas, R E; German, A J; Burgener, I A; Mandigers, P J J.
Affiliation
  • Hugen S; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
  • Thomas RE; Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
  • German AJ; School of Veterinary Science, University of Liverpool, Neston, UK.
  • Burgener IA; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
  • Mandigers PJJ; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Vet Comp Oncol ; 15(3): 692-705, 2017 Sep.
Article in En | MEDLINE | ID: mdl-27549077
ABSTRACT
Gastric carcinoma (GC) is the most common neoplasm in the stomach of dogs. Although incidence in the general population is reported to be low, breed-specific GC has a high incidence. Median age at presentation ranges from 8 to approximately 10 years. The disease is mostly located in the lesser curvature and antropyloric region of the stomach. Unfortunately, diagnosis is usually made when the disease is at an advanced stage and, therefore, prognosis is poor. Due to similarities in clinical presentation, diagnosis, histology and prognosis, canine GC may serve as a valuable model for human GC. Extensive pedigrees of canine gastric carcinoma cases could reveal insights for human gastric carcinoma. Putative species differences include the role of Helicobacter in pathogenesis, the wide array of genetic data and screening available for humans, and treatment protocols that are available for human GC.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Dog Diseases Type of study: Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Vet Comp Oncol Journal subject: MEDICINA VETERINARIA / NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Netherlands

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Dog Diseases Type of study: Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Vet Comp Oncol Journal subject: MEDICINA VETERINARIA / NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Netherlands