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Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors.
Connolly, Stuart J; Milling, Truman J; Eikelboom, John W; Gibson, C Michael; Curnutte, John T; Gold, Alex; Bronson, Michele D; Lu, Genmin; Conley, Pamela B; Verhamme, Peter; Schmidt, Jeannot; Middeldorp, Saskia; Cohen, Alexander T; Beyer-Westendorf, Jan; Albaladejo, Pierre; Lopez-Sendon, Jose; Goodman, Shelly; Leeds, Janet; Wiens, Brian L; Siegal, Deborah M; Zotova, Elena; Meeks, Brandi; Nakamya, Juliet; Lim, W Ting; Crowther, Mark.
Affiliation
  • Connolly SJ; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Milling TJ; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Eikelboom JW; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Gibson CM; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Curnutte JT; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Gold A; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Bronson MD; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Lu G; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Conley PB; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Verhamme P; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Schmidt J; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Middeldorp S; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Cohen AT; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Beyer-Westendorf J; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Albaladejo P; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Lopez-Sendon J; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Goodman S; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Leeds J; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Wiens BL; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Siegal DM; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Zotova E; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Meeks B; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Nakamya J; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Lim WT; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
  • Crowther M; From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C.,
N Engl J Med ; 375(12): 1131-41, 2016 09 22.
Article in En | MEDLINE | ID: mdl-27573206
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / Factor Xa / Factor Xa Inhibitors / Hemorrhage Type of study: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male Language: En Journal: N Engl J Med Year: 2016 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / Factor Xa / Factor Xa Inhibitors / Hemorrhage Type of study: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male Language: En Journal: N Engl J Med Year: 2016 Document type: Article