Phosphoinositide 3-kinase: a new kid on the block in vascular anomalies.

Castillo, Sandra D; Vanhaesebroeck, Bart; Sebire, Neil J

Castillo, Sandra D; Vanhaesebroeck, Bart; Sebire, Neil J.

Affiliation

Castillo SD; UCL Cancer Institute, University College London, London, UK.
Vanhaesebroeck B; UCL Cancer Institute, University College London, London, UK.
Sebire NJ; UCL Institute of Child Health & Great Ormond Street Hospital for Children, London, UK.

J Pathol ; 240(4): 387-396, 2016 12.

Article in En | MEDLINE | ID: mdl-27577520

Subject(s)

Phosphatidylinositol 3-Kinases/physiology; Vascular Malformations/enzymology; Vascular Neoplasms/enzymology; Humans; Molecular Targeted Therapy/methods; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction/physiology; Vascular Malformations/classification; Vascular Malformations/pathology; Vascular Malformations/therapy; Vascular Neoplasms/classification; Vascular Neoplasms/pathology; Vascular Neoplasms/therapy

Key words

AKT; PI3K; mTOR; signal transduction; targeted therapy; vascular anomaly; vascular malformation; vascular tumour

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vascular Neoplasms / Phosphatidylinositol 3-Kinases / Vascular Malformations Limits: Humans Language: En Journal: J Pathol Year: 2016 Document type: Article Country of publication: United kingdom

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