Chronic exposure to cannabinoids during adolescence causes long-lasting behavioral deficits in adult mice.

Tomas-Roig, J; Benito, E; Agis-Balboa, R C; Piscitelli, F; Hoyer-Fender, S; Di Marzo, V; Havemann-Reinecke, U

Tomas-Roig, J; Benito, E; Agis-Balboa, R C; Piscitelli, F; Hoyer-Fender, S; Di Marzo, V; Havemann-Reinecke, U.

Affiliation

Tomas-Roig J; Department of Psychiatry and Psychotherapy, University of Göttingen, Germany.
Benito E; Center Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), Germany.
Agis-Balboa RC; Research Group for Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases (DZNE), Germany.
Piscitelli F; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Germany.
Hoyer-Fender S; Instituto de Investigación Sanitaria Galicia Sur, Spain.
Di Marzo V; Endocannabinoid Research Group, Institute of Biomolecular Chemistry, Italy.
Havemann-Reinecke U; Johann-Friedrich-Blumenbach Institute for Zoology and Anthropology, Developmental Biology, Germany.

Addict Biol ; 22(6): 1778-1789, 2017 Nov.

Article in En | MEDLINE | ID: mdl-27578457

Subject(s)

Behavior, Animal/drug effects; Benzoxazines/pharmacology; Brain/drug effects; Memory Disorders/chemically induced; Morpholines/pharmacology; Naphthalenes/pharmacology; Animals; Cannabinoids/pharmacology; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL

Key words

Adolescence; CA regions; DNA methylation and Rgs7; WIN55212.2; learning and memory

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Behavior, Animal / Brain / Morpholines / Benzoxazines / Memory Disorders / Naphthalenes Type of study: Etiology_studies Limits: Animals Language: En Journal: Addict Biol Journal subject: TRANSTORNOS RELACIONADOS COM SUBSTANCIAS Year: 2017 Document type: Article Affiliation country: Germany Country of publication: United States

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