Label-free Raman spectroscopic imaging to extract morphological and chemical information from a formalin-fixed, paraffin-embedded rat colon tissue section.

Gaifulina, Riana; Maher, Andrew Thomas; Kendall, Catherine; Nelson, James; Rodriguez-Justo, Manuel; Lau, Katherine; Thomas, Geraint Mark

Gaifulina, Riana; Maher, Andrew Thomas; Kendall, Catherine; Nelson, James; Rodriguez-Justo, Manuel; Lau, Katherine; Thomas, Geraint Mark.

Affiliation

Gaifulina R; Department of Cell and Developmental Biology, University College London, London, UK.
Maher AT; Department of Cell and Developmental Biology, University College London, London, UK.
Kendall C; CoMPLEX, University College London, London, UK.
Nelson J; Biophotonics Research Unit, Gloucestershire Royal Hospital, Gloucester, UK.
Rodriguez-Justo M; Department of Statistical Science, University College London, London, UK.
Lau K; Department of Gastrointestinal Pathology, University College Hospital, London, UK.
Thomas GM; Spectroscopy Products Division, Renishaw Plc, Wotton-under-Edge, UK.

Int J Exp Pathol ; 97(4): 337-350, 2016 08.

Article in En | MEDLINE | ID: mdl-27581376

Subject(s)

Colon/anatomy & histology; Colon/chemistry; Spectrum Analysis, Raman/methods; Animals; Fixatives; Formaldehyde; Intestinal Mucosa/anatomy & histology; Intestinal Mucosa/chemistry; Paraffin Embedding/methods; Principal Component Analysis; Rats, Wistar; Tissue Fixation/methods

Key words

Raman microspectroscopy; biochemistry; formalin-fixed paraffin-embedded; haematoxylin and eosin; paraffin; principal component; rat colon

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spectrum Analysis, Raman / Colon Type of study: Guideline Limits: Animals Language: En Journal: Int J Exp Pathol Journal subject: PATOLOGIA Year: 2016 Document type: Article Affiliation country: United kingdom

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