Brain-Derived Neurotrophic Factor Facilitates Functional Recovery from ALS-Cerebral Spinal Fluid-Induced Neurodegenerative Changes in the NSC-34 Motor Neuron Cell Line.

Shruthi, Shanmukha; Sumitha, R; Varghese, Anu Mary; Ashok, S; Chandrasekhar Sagar, B K; Sathyaprabha, T N; Nalini, A; Kramer, Boris W; Raju, Trichur R; Vijayalakshmi, K; Alladi, Phalguni Anand

Shruthi, Shanmukha; Sumitha, R; Varghese, Anu Mary; Ashok, S; Chandrasekhar Sagar, B K; Sathyaprabha, T N; Nalini, A; Kramer, Boris W; Raju, Trichur R; Vijayalakshmi, K; Alladi, Phalguni Anand.

Affiliation

Shruthi S; Department of Neurophysiology, National Institute of Mental Health and Neurosciences, Bangalore, India.

Neurodegener Dis ; 17(1): 44-58, 2017.

Article in En | MEDLINE | ID: mdl-27617773

Subject(s)

Amyotrophic Lateral Sclerosis/cerebrospinal fluid; Brain-Derived Neurotrophic Factor/pharmacology; Motor Neurons/drug effects; Nerve Degeneration/drug therapy; Neuroprotective Agents/pharmacology; Recovery of Function/drug effects; Animals; Apoptosis/drug effects; Apoptosis/physiology; Brain-Derived Neurotrophic Factor/metabolism; Calcium/metabolism; Cell Line; Cell Survival/drug effects; Disease Models, Animal; Humans; Intermediate Filaments/drug effects; Intermediate Filaments/metabolism; Intermediate Filaments/pathology; Mice; Motor Neurons/physiology; Motor Neurons/ultrastructure; Nerve Degeneration/pathology; Nerve Degeneration/physiopathology; Rats, Wistar; Receptor, trkB/metabolism; Recovery of Function/physiology; Spinal Cord/drug effects; Spinal Cord/pathology; Spinal Cord/physiopathology

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Collection: 01-internacional Database: MEDLINE Main subject: Neuroprotective Agents / Brain-Derived Neurotrophic Factor / Recovery of Function / Amyotrophic Lateral Sclerosis / Motor Neurons / Nerve Degeneration Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Neurodegener Dis Journal subject: NEUROLOGIA Year: 2017 Document type: Article Affiliation country: India Country of publication: Switzerland

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