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Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.
Faulkner, Lee; Gibson, Andrew; Sullivan, Andrew; Tailor, Arun; Usui, Toru; Alfirevic, Ana; Pirmohamed, Munir; Naisbitt, Dean J; Kevin Park, B.
Affiliation
  • Faulkner L; Department of Molecular and Clinical Pharmacology, Centre for Drug Safety Science; bkpark@liverpool.ac.uk.
  • Gibson A; Department of Molecular and Clinical Pharmacology, Centre for Drug Safety Science; bkpark@liverpool.ac.uk.
  • Sullivan A; Department of Molecular and Clinical Pharmacology, Centre for Drug Safety Science; bkpark@liverpool.ac.uk.
  • Tailor A; Department of Molecular and Clinical Pharmacology, Centre for Drug Safety Science; bkpark@liverpool.ac.uk.
  • Usui T; Department of Molecular and Clinical Pharmacology, Centre for Drug Safety Science; bkpark@liverpool.ac.uk.
  • Alfirevic A; Department of Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK bkpark@liverpool.ac.uk.
  • Pirmohamed M; Department of Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK bkpark@liverpool.ac.uk.
  • Naisbitt DJ; Department of Molecular and Clinical Pharmacology, Centre for Drug Safety Science; bkpark@liverpool.ac.uk.
  • Kevin Park B; Department of Molecular and Clinical Pharmacology, Centre for Drug Safety Science; bkpark@liverpool.ac.uk.
Toxicol Sci ; 154(2): 416-429, 2016 12.
Article in En | MEDLINE | ID: mdl-27637899
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Collection: 01-internacional Database: MEDLINE Main subject: Sulfamethoxazole / Histocompatibility Testing / Leukocytes, Mononuclear / Lymphocyte Activation / T-Lymphocytes / Toxicity Tests / Drug Hypersensitivity / HLA Antigens Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2016 Document type: Article Country of publication: United States
Search on Google
Add to My VHL
Print
XML
PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Sulfamethoxazole / Histocompatibility Testing / Leukocytes, Mononuclear / Lymphocyte Activation / T-Lymphocytes / Toxicity Tests / Drug Hypersensitivity / HLA Antigens Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2016 Document type: Article Country of publication: United States