Comparative evaluation of antimicrobial efficacy of three different formulations of mouth rinses with multi-herbal mouth rinse.
J Indian Soc Pedod Prev Dent
; 34(4): 315-23, 2016.
Article
in En
| MEDLINE
| ID: mdl-27681394
ABSTRACT
CONTEXT In response to the propagation of various anti-Streptococcus preventive agents, the discovery of newer and more efficient agents which are more economical, efficacious, and safe are gaining popularity in today's era. AIMS:
The purpose was to compare the antimicrobial efficacy of multi-herbal mouth rinse with essential oil-based, fluoride containing, and 0.2% chlorhexidine digluconate mouth rinses, well-evidenced chemical formulations, against Streptococcus mutans. SETTINGS ANDDESIGN:
It is triple-blinded randomized controlled trial.METHODOLOGY:
One hundred and twenty adolescents aged between 15 and 17 years were randomized into four groups (a) multi-herbal mouth rinse, 15 ml twice a day; (b) 0.2% chlorhexidine mouth rinse, 15 ml twice a day; (c) essential oil mouth rinse, 15 ml twice a day (d) 0.2% sodium fluoride mouth rinse, twice a day. Salivary and plaque samples were collected from subjects and oral streptococci colony forming units (CFUs)/mL was assessed using TYCSB agar. STATISTICAL ANALYSIS USED Repeated measures of ANOVA were used to compare the various mouthrinses followed by post hoc Bonferroni test for comparing multi-herbal mouthrinse with other mouthrinses. Significance was set at P < 0.05.RESULTS:
At baseline, there was no statistically significant difference in the distribution of baseline data groups, but reduction of S. mutans colony count of multi-herbal mouth rinse in comparison with the other mouthrinses had statistically significant values except Fluoride mouth rinse till 1 week postrinsing.CONCLUSION:
Chlorhexidine and multi-herbal mouth rinses showed statistically significant reduction in the S. mutans CFU count, in terms of efficacy and substantivity both.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Streptococcus mutans
/
Herbal Medicine
/
Phytotherapy
/
Anti-Infective Agents, Local
/
Mouthwashes
Type of study:
Clinical_trials
Limits:
Adolescent
/
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
J Indian Soc Pedod Prev Dent
Journal subject:
ODONTOLOGIA
Year:
2016
Document type:
Article
Affiliation country:
India
Publication country:
IN
/
INDIA
/
ÍNDIA