Susceptibility of Select Agents to Predation by Predatory Bacteria.
Microorganisms
; 3(4): 903-12, 2015 Dec 02.
Article
in En
| MEDLINE
| ID: mdl-27682124
ABSTRACT
Select Agents are microorganisms and toxins considered to be exploitable as biological weapons. Although infections by many Select Agents can be treated by conventional antibiotics, the risk of an emerging or engineered drug resistant strain is of great concern. One group of microorganisms that is showing potential to control drug resistant Gram-negative bacteria are the predatory bacteria from the genera Bdellovibrio spp. and Micavibrio spp. In this study, we have examined the ability of Bdellovibrio bacteriovorus (B. bacteriovorus) strain 109J, HD100 and Micavibrio aeruginosavorus (M. aeruginosavorus) ARL-13 to prey on a variety of Select Agents. Our findings demonstrate that B. bacteriovorus and M. aeruginosavorus are able to prey efficiently on Yersinia pestis and Burkholderia mallei. Modest predation was also measured in co-cultures of B. bacteriovorus and Francisella tularensis. However, neither of the predators showed predation when Burkholderia pseudomallei and Brucella melitensis were used as prey.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Microorganisms
Year:
2015
Document type:
Article
Affiliation country:
United States