Toxic polyacetylenes in the genus Bupleurum (Apiaceae) - Distribution, toxicity, molecular mechanism and analysis.

Lin, Meiyu; Zhang, Weidong; Su, Juan

Lin, Meiyu; Zhang, Weidong; Su, Juan.

Affiliation

Lin M; School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
Zhang W; School of Pharmacy, Second Military Medical University, Shanghai 200433, China. Electronic address: juansu_2008@126.com.
Su J; School of Pharmacy, Second Military Medical University, Shanghai 200433, China. Electronic address: juansu_2008@126.com.

J Ethnopharmacol ; 193: 566-573, 2016 Dec 04.

Article in En | MEDLINE | ID: mdl-27693772

Subject(s)

Bupleurum/chemistry; Plant Extracts/isolation & purification; Plant Extracts/toxicity; Polyynes/isolation & purification; Polyynes/toxicity; Animals; Biomarkers/analysis; Bupleurum/growth & development; Bupleurum/toxicity; Dose-Response Relationship, Drug; Humans; Lethal Dose 50; Medicine, Traditional; Plant Extracts/pharmacology; Polyynes/pharmacology

Key words

Bupleurum; Mechanism; Polyacetylenes; Quality analyses; Toxicity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Bupleurum / Polyynes Type of study: Qualitative_research Limits: Animals / Humans Language: En Journal: J Ethnopharmacol Year: 2016 Document type: Article Affiliation country: China Country of publication: Ireland

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