Phosphatidic acid induces decidualization by stimulating Akt-PP2A binding in human endometrial stromal cells.

Lee, So Young; Lee, Yun Young; Choi, Joong Sub; Yoon, Mee-Sup; Han, Joong-Soo

Lee, So Young; Lee, Yun Young; Choi, Joong Sub; Yoon, Mee-Sup; Han, Joong-Soo.

Affiliation

Lee SY; Department of Biomedical Sciences, Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul, Korea.
Lee YY; Department of Biomedical Sciences, Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul, Korea.
Choi JS; Department of Obstetrics and Gynecology, College of Medicine, Hanyang University, Seoul, Korea.
Yoon MS; Department of Molecular Medicine, School of Medicine, Gachon University, Incheon, Korea.
Han JS; Department of Biomedical Sciences, Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul, Korea.

FEBS J ; 283(22): 4163-4175, 2016 11.

Article in En | MEDLINE | ID: mdl-27696687

Subject(s)

Decidua/drug effects; Endometrium/cytology; Phosphatidic Acids/pharmacology; Protein Phosphatase 2/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Stromal Cells/drug effects; Adult; Blotting, Western; Cells, Cultured; Cyclic AMP/pharmacology; Decidua/metabolism; Female; Forkhead Box Protein O1/metabolism; Gene Expression/drug effects; Humans; Insulin-Like Growth Factor Binding Protein 1/genetics; Middle Aged; Okadaic Acid/pharmacology; Phospholipase D/genetics; Phospholipase D/metabolism; Phosphorylation/drug effects; Prolactin/genetics; Protein Binding/drug effects; Protein Phosphatase 2/antagonists & inhibitors; RNA Interference; Reverse Transcriptase Polymerase Chain Reaction; Stromal Cells/metabolism

Key words

decidualization; human endometrial stromal cells; infertility; phosphatidic acid; phospholipase D1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphatidic Acids / Stromal Cells / Decidua / Endometrium / Proto-Oncogene Proteins c-akt / Protein Phosphatase 2 Limits: Adult / Female / Humans / Middle aged Language: En Journal: FEBS J Journal subject: BIOQUIMICA Year: 2016 Document type: Article

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