Integrins and heparan sulfate proteoglycans on hepatic stellate cells (HSC) are novel receptors for HSC-derived exosomes.

Chen, Li; Brigstock, David R

Chen, Li; Brigstock, David R.

Affiliation

Chen L; The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Brigstock DR; The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.

FEBS Lett ; 590(23): 4263-4274, 2016 Dec.

Article in En | MEDLINE | ID: mdl-27714787

Subject(s)

Exosomes/metabolism; Heparan Sulfate Proteoglycans/pharmacology; Hepatic Stellate Cells/cytology; Hepatic Stellate Cells/metabolism; Integrins/metabolism; Animals; Exosomes/drug effects; Heparin/pharmacology; Hepatic Stellate Cells/drug effects; Mice

Key words

connective tissue growth factor; fibrogenesis; hepatic fibrosis; microRNA; microvesicle

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Integrins / Heparan Sulfate Proteoglycans / Exosomes / Hepatic Stellate Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: FEBS Lett Year: 2016 Document type: Article Affiliation country: United States Country of publication: United kingdom

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