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Ketamine up-regulates a cluster of intronic miRNAs within the serotonin receptor 2C gene by inhibiting glycogen synthase kinase-3.
Grieco, Steven F; Velmeshev, Dmitry; Magistri, Marco; Eldar-Finkelman, Hagit; Faghihi, Mohammad A; Jope, Richard S; Beurel, Eleonore.
Affiliation
  • Grieco SF; a Department of Psychiatry and Behavioural Sciences , Miller School of Medicine, University of Miami , Miami , FL , USA.
  • Velmeshev D; b Department of Biochemistry and Molecular Biology , Miller School of Medicine, University of Miami , Miami , FL , USA.
  • Magistri M; a Department of Psychiatry and Behavioural Sciences , Miller School of Medicine, University of Miami , Miami , FL , USA.
  • Eldar-Finkelman H; b Department of Biochemistry and Molecular Biology , Miller School of Medicine, University of Miami , Miami , FL , USA.
  • Faghihi MA; a Department of Psychiatry and Behavioural Sciences , Miller School of Medicine, University of Miami , Miami , FL , USA.
  • Jope RS; b Department of Biochemistry and Molecular Biology , Miller School of Medicine, University of Miami , Miami , FL , USA.
  • Beurel E; c Department of Human Molecular Genetics and Biochemistry , Sackler School of Medicine, Tel Aviv University , Tel Aviv , Israel.
World J Biol Psychiatry ; 18(6): 445-456, 2017 09.
Article in En | MEDLINE | ID: mdl-27723376
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Behavior, Animal / Introns / Glycogen Synthase Kinase 3 / MicroRNAs / Receptor, Serotonin, 5-HT2C / Protein Kinase Inhibitors / Hippocampus / Ketamine / Antidepressive Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: World J Biol Psychiatry Journal subject: PSIQUIATRIA Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Behavior, Animal / Introns / Glycogen Synthase Kinase 3 / MicroRNAs / Receptor, Serotonin, 5-HT2C / Protein Kinase Inhibitors / Hippocampus / Ketamine / Antidepressive Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: World J Biol Psychiatry Journal subject: PSIQUIATRIA Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom