Your browser doesn't support javascript.
loading
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis.
Singh, Vinayak; Donini, Stefano; Pacitto, Angela; Sala, Claudia; Hartkoorn, Ruben C; Dhar, Neeraj; Keri, Gyorgy; Ascher, David B; Mondésert, Guillaume; Vocat, Anthony; Lupien, Andréanne; Sommer, Raphael; Vermet, Hélène; Lagrange, Sophie; Buechler, Joe; Warner, Digby F; McKinney, John D; Pato, Janos; Cole, Stewart T; Blundell, Tom L; Rizzi, Menico; Mizrahi, Valerie.
Affiliation
  • Singh V; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine & Department of Pathology, University of Cape Town , Anzio Road, Observatory 7925, South Africa.
  • Donini S; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale , Via Bovio 6, 28100 Novara, Italy.
  • Pacitto A; Department of Biochemistry, University of Cambridge , 80 Tennis Court Road, Cambridge CB2 1GA, United Kingdom.
  • Sala C; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
  • Hartkoorn RC; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
  • Dhar N; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
  • Keri G; Vichem Chemie , Herman Ottó út 15, Budapest, 1022 Hungary.
  • Ascher DB; Department of Biochemistry, University of Cambridge , 80 Tennis Court Road, Cambridge CB2 1GA, United Kingdom.
  • Mondésert G; Sanofi-Aventis Research & Development , Infectious Diseases Unit, Biology Group, Campus Mérieux, 1541 avenue Marcel Mérieux, 69280 Marcy L'Etoile, France.
  • Vocat A; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
  • Lupien A; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
  • Sommer R; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
  • Vermet H; Sanofi-Aventis Research & Development , Infectious Diseases Unit, Biology Group, Campus Mérieux, 1541 avenue Marcel Mérieux, 69280 Marcy L'Etoile, France.
  • Lagrange S; Sanofi-Aventis Research & Development , Infectious Diseases Unit, Biology Group, Campus Mérieux, 1541 avenue Marcel Mérieux, 69280 Marcy L'Etoile, France.
  • Buechler J; Alere (San Diego) , Summer Ridge Road, San Diego, California 92121, United States.
  • Warner DF; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine & Department of Pathology, University of Cape Town , Anzio Road, Observatory 7925, South Africa.
  • McKinney JD; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
  • Pato J; Vichem Chemie , Herman Ottó út 15, Budapest, 1022 Hungary.
  • Cole ST; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute , Station 19, 1015 Lausanne, Switzerland.
  • Blundell TL; Department of Biochemistry, University of Cambridge , 80 Tennis Court Road, Cambridge CB2 1GA, United Kingdom.
  • Rizzi M; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale , Via Bovio 6, 28100 Novara, Italy.
  • Mizrahi V; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine & Department of Pathology, University of Cape Town , Anzio Road, Observatory 7925, South Africa.
ACS Infect Dis ; 3(1): 5-17, 2017 01 13.
Article in En | MEDLINE | ID: mdl-27726334

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfones / Tuberculosis / IMP Dehydrogenase / Mycobacterium / Antitubercular Agents Limits: Animals Language: En Journal: ACS Infect Dis Year: 2017 Document type: Article Affiliation country: South Africa Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfones / Tuberculosis / IMP Dehydrogenase / Mycobacterium / Antitubercular Agents Limits: Animals Language: En Journal: ACS Infect Dis Year: 2017 Document type: Article Affiliation country: South Africa Country of publication: United States