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HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer.
Ross-Adams, Helen; Ball, Stephen; Lawrenson, Kate; Halim, Silvia; Russell, Roslin; Wells, Claire; Strand, Siri H; Ørntoft, Torben F; Larson, Melissa; Armasu, Sebastian; Massie, Charles E; Asim, Mohammad; Mortensen, Martin M; Borre, Michael; Woodfine, Kathryn; Warren, Anne Y; Lamb, Alastair D; Kay, Jonathan; Whitaker, Hayley; Ramos-Montoya, Antonio; Murrell, Adele; Sørensen, Karina D; Fridley, Brooke L; Goode, Ellen L; Gayther, Simon A; Masters, John; Neal, David E; Mills, Ian G.
Affiliation
  • Ross-Adams H; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Ball S; Prostate Cancer Research Centre, University College London, London, UK.
  • Lawrenson K; Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.
  • Halim S; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Russell R; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Wells C; Division of Cancer Studies, King's College London, London, UK.
  • Strand SH; Department of Molecular Medicine, Aarhus University Hospital, Denmark.
  • Ørntoft TF; Department of Molecular Medicine, Aarhus University Hospital, Denmark.
  • Larson M; Mayo Clinic, SW Rochester, MN, USA.
  • Armasu S; Mayo Clinic, SW Rochester, MN, USA.
  • Massie CE; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Asim M; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Mortensen MM; Department of Urology, Aarhus University Hospital, Aarhus, Denmark.
  • Borre M; Department of Urology, Aarhus University Hospital, Aarhus, Denmark.
  • Woodfine K; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Warren AY; Department of Pathology, Addenbrooke's Hospital, Cambridge, UK.
  • Lamb AD; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Kay J; Department of Urology, Addenbrooke's Hospital, Cambridge, UK.
  • Whitaker H; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Ramos-Montoya A; Molecular Diagnostics and Therapeutics Group, University College London, London, UK.
  • Murrell A; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Sørensen KD; Molecular Diagnostics and Therapeutics Group, University College London, London, UK.
  • Fridley BL; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Goode EL; Department of Biology and Biochemistry, University of Bath, Centre for Regenerative Medicine, Claverton Down, Bath, UK.
  • Gayther SA; Department of Molecular Medicine, Aarhus University Hospital, Denmark.
  • Masters J; Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS, USA.
  • Neal DE; Mayo Clinic, SW Rochester, MN, USA.
  • Mills IG; Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Oncotarget ; 7(46): 74734-74746, 2016 11 15.
Article in En | MEDLINE | ID: mdl-27732966

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Prostatic Neoplasms / Gene Expression Regulation, Neoplastic / Promoter Regions, Genetic / DNA Methylation / Hepatocyte Nuclear Factor 1-beta / Gene Regulatory Networks Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Oncotarget Year: 2016 Document type: Article Affiliation country: United kingdom Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Prostatic Neoplasms / Gene Expression Regulation, Neoplastic / Promoter Regions, Genetic / DNA Methylation / Hepatocyte Nuclear Factor 1-beta / Gene Regulatory Networks Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Oncotarget Year: 2016 Document type: Article Affiliation country: United kingdom Country of publication: United States