The RNA-binding landscape of RBM10 and its role in alternative splicing regulation in models of mouse early development.

Rodor, Julie; FitzPatrick, David R; Eyras, Eduardo; Cáceres, Javier F

Rodor, Julie; FitzPatrick, David R; Eyras, Eduardo; Cáceres, Javier F.

Affiliation

Rodor J; a Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital , Edinburgh , EH4 2XU , UK.
FitzPatrick DR; a Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital , Edinburgh , EH4 2XU , UK.
Eyras E; b Computational Genomics Group, Universitat Pompeu Fabra , E08003 , Barcelona , Spain.
Cáceres JF; c Catalan Institution for Research and Advanced Studies (ICREA) , E08010 , Barcelona , Spain.

RNA Biol ; 14(1): 45-57, 2017 01 02.

Article in En | MEDLINE | ID: mdl-27763814

Subject(s)

Alternative Splicing; Embryonic Development/genetics; Gene Expression Regulation; RNA-Binding Proteins/metabolism; Animals; Binding Sites; Chromosome Mapping; Embryonic Stem Cells/metabolism; Female; Gene Knockout Techniques; Genome-Wide Association Study; High-Throughput Nucleotide Sequencing; Male; Mice; Molecular Sequence Annotation; Nucleotide Motifs; Phenotype; Protein Binding; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Small Nuclear/genetics; RNA, Small Nuclear/metabolism; Spliceosomes/metabolism

Key words

Alternative splicing; RBM10; RNA-binding proteins; TARP syndrome; iCLIP; mandibular cell line; stem cells

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / RNA-Binding Proteins / Alternative Splicing / Embryonic Development Limits: Animals Language: En Journal: RNA Biol Journal subject: BIOLOGIA MOLECULAR Year: 2017 Document type: Article Affiliation country: United kingdom

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