Emerging Skin T-Cell Functions in Response to Environmental Insults.
J Invest Dermatol
; 137(2): 288-294, 2017 02.
Article
in En
| MEDLINE
| ID: mdl-27784595
ABSTRACT
Skin is the primary barrier between the body and the outside world, functioning not only as a physical barrier, but also as an immunologic first line of defense. A large number of T cells populate the skin. This review highlights the ability of these cutaneous T cells to regulate skin-specific environmental threats, including microbes, injuries, solar UV radiation, and allergens. Since much of this knowledge has been advanced from murine studies, we focus our review on how the mouse state has informed the human state, emphasizing the key parallels and differences.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin
/
T-Lymphocytes
Type of study:
Etiology_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
J Invest Dermatol
Year:
2017
Document type:
Article
Affiliation country:
United States