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Tilting the balance between RNA interference and replication eradicates Leishmania RNA virus 1 and mitigates the inflammatory response.
Brettmann, Erin A; Shaik, Jahangheer S; Zangger, Haroun; Lye, Lon-Fye; Kuhlmann, F Matthew; Akopyants, Natalia S; Oschwald, Dayna M; Owens, Katherine L; Hickerson, Suzanne M; Ronet, Catherine; Fasel, Nicolas; Beverley, Stephen M.
Affiliation
  • Brettmann EA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.
  • Shaik JS; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.
  • Zangger H; Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland.
  • Lye LF; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.
  • Kuhlmann FM; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Akopyants NS; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.
  • Oschwald DM; Genome Technology Access Center, Washington University School of Medicine, St. Louis, MO 63110.
  • Owens KL; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.
  • Hickerson SM; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.
  • Ronet C; Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland.
  • Fasel N; Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland.
  • Beverley SM; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110; stephen.beverley@wustl.edu.
Proc Natl Acad Sci U S A ; 113(43): 11998-12005, 2016 10 25.
Article in En | MEDLINE | ID: mdl-27790981

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Double-Stranded / RNA, Viral / Leishmaniasis, Mucocutaneous / Leishmaniavirus / Oligoribonucleotides, Antisense / Antiprotozoal Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2016 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Double-Stranded / RNA, Viral / Leishmaniasis, Mucocutaneous / Leishmaniavirus / Oligoribonucleotides, Antisense / Antiprotozoal Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2016 Document type: Article