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Metabolic Control of Cellular Differentiation.
Bulusu, Vinay; Aulehla, Alexander.
Affiliation
  • Bulusu V; Cancer Metabolism Research Unit, Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK.
  • Aulehla A; Developmental Biology Unit, European Molecular Biology Laboratory, Meyerhofstraße 1, Heidelberg 69117, Germany. Electronic address: aulehla@embl.de.
Dev Cell ; 39(3): 286-287, 2016 11 07.
Article in En | MEDLINE | ID: mdl-27825439
The role of metabolic rewiring during cellular differentiation is under intense investigation. Reporting recently in Science, Peng et al. (2016) found that activation of glycolysis supports T helper cell differentiation by controlling acetyl-coA and histone acetylation levels, identifying a link between metabolic state and epigenetic control of gene activity.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acetyl Coenzyme A / Histones Language: En Journal: Dev Cell Journal subject: EMBRIOLOGIA Year: 2016 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acetyl Coenzyme A / Histones Language: En Journal: Dev Cell Journal subject: EMBRIOLOGIA Year: 2016 Document type: Article Country of publication: United States