F-THENA: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system.
Org Biomol Chem
; 14(46): 11002-11012, 2016 Nov 22.
Article
in En
| MEDLINE
| ID: mdl-27827507
ABSTRACT
F-THENA is designed as an alternative fluorine-containing chiral derivatizing agent (CDA). The fluorine atom functions exclusively as a reporter which can directly sense an anisotropic effect from an aromatic substituent of a chiral alcohol. In combination with chemical shift differences from both 19F NMR and 1H NMR, the F-THENA method can successfully be used for determining the absolute configuration of chiral secondary aromatic alcohols with a self-validating system.
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Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Org Biomol Chem
Journal subject:
BIOQUIMICA
/
QUIMICA
Year:
2016
Document type:
Article
Affiliation country:
Thailand