Managing Innovation to Maximize Value Along the Discovery-Translation-Application Continuum.
Clin Pharmacol Ther
; 101(1): 8-12, 2017 Jan.
Article
in En
| MEDLINE
| ID: mdl-27869291
ABSTRACT
Success in pharmaceutical development led to a record 51 drugs approved in the past year, surpassing every previous year since 1950. Technology innovation enabled identification and exploitation of increasingly precise disease targets ensuring next generation diagnostic and therapeutic products for patient management. The expanding biopharmaceutical portfolio stands, however, in contradistinction to the unsustainable costs that reflect remarkable challenges of clinical development programs. This annual Therapeutic Innovations issue juxtaposes advances in translating molecular breakthroughs into transformative therapies with essential considerations for lowering attrition and improving the cost-effectiveness of the drug-development paradigm. Realizing the discovery-translation-application continuum mandates a congruent approval, adoption, and access triad.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Drug Design
/
Drug Approval
/
Drug Discovery
/
Translational Research, Biomedical
Type of study:
Sysrev_observational_studies
Limits:
Humans
Language:
En
Journal:
Clin Pharmacol Ther
Year:
2017
Document type:
Article
Affiliation country:
United States