Prognostic value of post-Yttrium 90 radioembolization therapy 18F-fluorodeoxyglucose positron emission tomography in patients with liver tumors.
Clin Imaging
; 42: 43-49, 2017.
Article
in En
| MEDLINE
| ID: mdl-27875761
ABSTRACT
OBJECTIVE:
This study assessed the benefit of post-therapy 18F-FDG PET/CT versus CT alone in identifying malignant liver tumor progression following radioembolization with Y-90 microspheres.METHODS:
24 patients with 44 liver tumors underwent CT imaging pre-radioembolization and PET/CT post-radioembolization. Predictive value of Response Evaluation Criteria in Solid Tumors (RECIST 1.1), The World Health Organization (WHO), mRECIST and European Association for the Study of the Liver (EASL) with PET/CT versus CT alone was assessed.RESULTS:
Prediction of liver malignancy progression was improved (p<0.05) for tumors labeled as non-responding based on combined PET/CT with RECIST 1.1, WHO, mRECIST, and EASL criteria compared to assessment without PET.CONCLUSIONS:
The addition of post-therapy PET to routine CT in patients with hepatic tumors undergoing radioembolization may improve identification of non-responding tumors.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Yttrium Radioisotopes
/
Brachytherapy
/
Radiopharmaceuticals
/
Embolization, Therapeutic
/
Positron Emission Tomography Computed Tomography
/
Liver Neoplasms
Type of study:
Prognostic_studies
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Clin Imaging
Journal subject:
DIAGNOSTICO POR IMAGEM
Year:
2017
Document type:
Article
Affiliation country:
United States