Prenatal cfDNA screening results indicative of maternal neoplasm: survey of current practice and management needs.
Prenat Diagn
; 37(2): 126-132, 2017 Feb.
Article
in En
| MEDLINE
| ID: mdl-27878832
ABSTRACT
OBJECTIVE:
To determine genetic counselors' current practices and management needs for patients with prenatal cfDNA screening results indicative of maternal neoplasm.METHODS:
A survey was completed by genetic counselors recruited via the National Society of Genetic Counselors (NSGC).RESULTS:
Over 300 genetic counselors were surveyed. Almost all participants (95%) were aware that Noninvasive Prenatal Testing (NIPT) results may suggest maternal neoplasm, and 77% reported they would disclose such results. However, only 29% routinely communicate this possibility to patients in a pre-test setting. Management recommendations made by counselors were highly variable, and over half (51.8%) stated they would feel uncomfortable or very uncomfortable counseling a patient with these results. While less than half (44.3%) believed the current benefits of NIPT's ability to suggest maternal neoplasm outweigh its potential harms, 80.2% recognized it would be beneficial in the future. A vast majority of counselors (91.3%) felt institutional or national guidelines were needed for patient management.CONCLUSION:
A majority of counselors neither felt properly equipped nor comfortable counseling patients with prenatal cfDNA results suggestive of maternal neoplasm. This study demonstrates a need for collaboration amongst clinicians, researchers, and laboratories to publish data regarding NIPT results indicative of maternal neoplasm, and for the creation of management guidelines. © 2016 John Wiley & Sons, Ltd.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pregnancy Complications, Neoplastic
/
Prenatal Diagnosis
/
Practice Patterns, Physicians'
/
DNA, Neoplasm
/
Attitude of Health Personnel
/
Genetic Counseling
/
Health Services Needs and Demand
Type of study:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
/
Qualitative_research
/
Screening_studies
Limits:
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
Prenat Diagn
Year:
2017
Document type:
Article
Affiliation country:
United States