Outbreak of severe pseudorabies virus infection in pig-offal-fed farmed mink in Liaoning Province, China.
Arch Virol
; 162(3): 863-866, 2017 Mar.
Article
in En
| MEDLINE
| ID: mdl-27885561
ABSTRACT
An outbreak of severe pseudorabies virus (PRV) infection in farmed mink occurred in northern China in late 2014, causing significant economic losses in the local fur industry. Here, we report the first case of a PRV outbreak in mink in northeastern China, caused by feeding farmed mink with raw pork or organs contaminated by PRV. Mink infected with virulent PRV exhibited diarrhea, neurologic signs, and higher mortality, which can be misdiagnosed as highly pathogenic mink enteritis virus (MEV), canine distemper virus (CDV), and food poisoning. However, these were excluded as causative agents by PCR or bacteria isolation. The duration of disease was 3-7 days, and the mortality rate was 80-90%. PRV was characterized using indirect immunofluorescence assays (IFA) and electron microscopy (EM). Phylogenetic analysis based on full-length genome sequences and those of individual genes of this novel virus strain showed that it clustered in an independent branch with several other PRV isolates from China.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pseudorabies
/
Herpesvirus 1, Suid
/
Animal Feed
/
Mink
Limits:
Animals
Country/Region as subject:
Asia
Language:
En
Journal:
Arch Virol
Year:
2017
Document type:
Article
Affiliation country:
China
Publication country:
AT
/
AUSTRIA
/
ÁUSTRIA