Roles of 1,25(OH)2D3 and Vitamin D Receptor in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus by Regulating the Activation of CD4+ T Cells and the PKCÎ´/ERK Signaling Pathway.

He, Xiao-Jie; Ding, Yan; Xiang, Wei; Dang, Xi-Qiang

He, Xiao-Jie; Ding, Yan; Xiang, Wei; Dang, Xi-Qiang.

Affiliation

He XJ; Department of Pediatrics, the Second Xiangya Hospital, Central South University, Changsha, P.R. China.

Cell Physiol Biochem ; 40(3-4): 743-756, 2016.

Article in En | MEDLINE | ID: mdl-27915349

Subject(s)

Arthritis, Rheumatoid/immunology; CD4-Positive T-Lymphocytes/immunology; Lupus Erythematosus, Systemic/immunology; Lymphocyte Activation/immunology; MAP Kinase Signaling System; Protein Kinase C-delta/metabolism; Receptors, Calcitriol/metabolism; Adult; Antigens, CD/metabolism; Arthritis, Rheumatoid/blood; Arthritis, Rheumatoid/genetics; Calcitriol/blood; Calcitriol/pharmacology; Case-Control Studies; DNA Methylation/genetics; Female; Gene Expression Regulation; Genetic Vectors/metabolism; Humans; Lupus Erythematosus, Systemic/blood; Lupus Erythematosus, Systemic/genetics; Male; Protein Kinase C-delta/genetics; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Small Interfering/metabolism; Receptors, Calcitriol/genetics; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Lymphocyte Activation / CD4-Positive T-Lymphocytes / Receptors, Calcitriol / MAP Kinase Signaling System / Protein Kinase C-delta / Lupus Erythematosus, Systemic Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: Cell Physiol Biochem Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2016 Document type: Article

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