The relationship between serum vitamin D level and premenstrual syndrome in Iranian women.
Int J Reprod Biomed
; 14(10): 665-668, 2016 Oct.
Article
in En
| MEDLINE
| ID: mdl-27921091
ABSTRACT
BACKGROUND:
Premenstrual syndrome (PMS) is among the most unfavorable problems in women in reproductive age; however its pathophysiology is still not fully confirmed. Vitamin D as an immunomodulator could prevent inflammatory state before and during menstruation.OBJECTIVE:
The aim was to investigate whether there is any relationship between serum vitamin D levels and PMS. MATERIALS ANDMETHODS:
In total, 82 women participate in this case-control study which was conducted in Shahid Akbar-abadi hospital from November 2013 to March 2015. Categorization was based on an Iranian version of the premenstrual symptoms screening tool (PSST). Levels of 25 hydroxy-vitamin D3 (25OHD) were determined by using 25-OH Vitamin D ELISA kit in luteal phase. Characteristics of participants and vitamin D levels were compared between two groups by using independent sample t-test.RESULTS:
Menarche age of women with PMS was significantly lower than normal women (p=0.04). Body mass index was not statistically different between groups. We observed a high rate of vitamin D deficiency and also its severe deficiency in both PMS and non-PMS groups. However, our study demonstrated no significant difference in the levels of serum 25OHD between the two groups.CONCLUSION:
It seems there is no association between PMS and serum levels of vitamin D3; however, the high rate of vitamin D deficiency among young Iranian women emerges special health care considerations in this group.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Observational_studies
/
Risk_factors_studies
Language:
En
Journal:
Int J Reprod Biomed
Year:
2016
Document type:
Article
Affiliation country:
Iran