LIM domain-binding 1 maintains the terminally differentiated state of pancreatic ß cells.

Ediger, Benjamin N; Lim, Hee-Woong; Juliana, Christine; Groff, David N; Williams, LaQueena T; Dominguez, Giselle; Liu, Jin-Hua; Taylor, Brandon L; Walp, Erik R; Kameswaran, Vasumathi; Yang, Juxiang; Liu, Chengyang; Hunter, Chad S; Kaestner, Klaus H; Naji, Ali; Li, Changhong; Sander, Maike; Stein, Roland; Sussel, Lori; Won, Kyoung-Jae; May, Catherine Lee; Stoffers, Doris A

Ediger, Benjamin N; Lim, Hee-Woong; Juliana, Christine; Groff, David N; Williams, LaQueena T; Dominguez, Giselle; Liu, Jin-Hua; Taylor, Brandon L; Walp, Erik R; Kameswaran, Vasumathi; Yang, Juxiang; Liu, Chengyang; Hunter, Chad S; Kaestner, Klaus H; Naji, Ali; Li, Changhong; Sander, Maike; Stein, Roland; Sussel, Lori; Won, Kyoung-Jae; May, Catherine Lee; Stoffers, Doris A.

J Clin Invest ; 127(1): 215-229, 2017 01 03.

Article in En | MEDLINE | ID: mdl-27941246

Subject(s)

Cell Differentiation; DNA-Binding Proteins/metabolism; Insulin-Secreting Cells/metabolism; LIM Domain Proteins/metabolism; Transcription Factors/metabolism; Animals; Basic Helix-Loop-Helix Transcription Factors/genetics; Basic Helix-Loop-Helix Transcription Factors/metabolism; DNA-Binding Proteins/genetics; Diabetes Mellitus, Type 2/genetics; Diabetes Mellitus, Type 2/metabolism; Diabetes Mellitus, Type 2/pathology; Hepatocyte Nuclear Factor 3-beta/genetics; Hepatocyte Nuclear Factor 3-beta/metabolism; Homeobox Protein Nkx-2.2; Homeodomain Proteins/genetics; Homeodomain Proteins/metabolism; Humans; Insulin-Secreting Cells/pathology; LIM Domain Proteins/genetics; LIM-Homeodomain Proteins/genetics; LIM-Homeodomain Proteins/metabolism; Mice; Mice, Transgenic; Nerve Tissue Proteins/genetics; Nerve Tissue Proteins/metabolism; Nuclear Proteins; Trans-Activators/genetics; Trans-Activators/metabolism; Transcription Factors/genetics; Zebrafish Proteins

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Cell Differentiation / DNA-Binding Proteins / Insulin-Secreting Cells / LIM Domain Proteins Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2017 Document type: Article

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